Opportunity Information: Apply for PAR 25 414
The Support for Research Excellence (SuRE) Award (R16, Clinical Trial Not Allowed) is a National Institutes of Health (NIH) grant opportunity designed to strengthen research capacity at eligible, resource-limited colleges and universities. It funds investigator-initiated biomedical research projects that align with NIH mission areas and can span basic, social, clinical (non-trial), behavioral, or translational science. A central aim is to build sustainable research programs and a stronger scientific culture at institutions that have fewer research resources, while supporting meaningful research opportunities for students.
This program is specifically aimed at full-time faculty investigators who do not currently hold NIH Research Project Grant (RPG) funding, with the only exception being current or prior SuRE or SuRE-First support. In other words, it is intended to broaden participation in NIH-funded research by backing investigators who are not already supported by standard NIH RPG mechanisms. Beyond producing scientific findings, SuRE places strong emphasis on workforce and institutional development: proposals should be structured in a way that creates high-quality research experiences for undergraduate and/or graduate students and contributes to a more vibrant, research-active campus environment.
Eligibility is limited to U.S.-based institutions of higher education, including public and state-controlled universities as well as private universities and colleges. Foreign organizations are not eligible to apply, and the program also prohibits non-U.S. components of U.S. organizations. In addition, foreign components (as defined by the NIH Grants Policy Statement) are not allowed, meaning the work supported under this award must remain domestically based rather than relying on international performance sites or foreign subcomponents.
Administratively, this opportunity is a discretionary NIH grant (Funding Instrument: Grant) under Funding Opportunity Number PAR-25-414. It is associated with multiple NIH CFDA/assistance listing numbers (93.113, 93.121, 93.172, 93.173, 93.242, 93.273, 93.279, 93.286, 93.307, 93.361, 93.398, 93.846, 93.847, 93.853, 93.855, 93.859, 93.865, 93.866, 93.867, 93.879), reflecting that it can support research relevant to a wide range of NIH institutes and mission areas. The listed award ceiling is $100,000. The opportunity was created on 2025-06-13, and the current closing date is 2028-09-07. Clinical trials are not allowed under this announcement, so proposed clinical research must remain outside the NIH definition of a clinical trial.
Overall, SuRE (R16) is best understood as a capacity-building research grant: it supports a defined biomedical research project while intentionally developing investigator independence at under-resourced institutions, expanding student training and participation in research, and strengthening long-term institutional research infrastructure and culture within the United States.Apply for PAR 25 414
- The National Institutes of Health in the education, environment, food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "Support for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.172, 93.173, 93.242, 93.273, 93.279, 93.286, 93.307, 93.361, 93.398, 93.846, 93.847, 93.853, 93.855, 93.859, 93.865, 93.866, 93.867, 93.879.
- This funding opportunity was created on 2025-06-13.
- Applicants must submit their applications by 2028-09-07.
- Each selected applicant is eligible to receive up to $100,000.00 in funding.
- Eligible applicants include: Public and State controlled institutions of higher education, Private institutions of higher education.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 25 414) also looked into and applied for these:
| Funding Opportunity |
|---|
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 25 425 Funding Number: PA 25 425 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32) Apply for PA 25 423 Funding Number: PA 25 423 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 25 426 Funding Number: PA 25 426 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) Apply for PA 25 422 Funding Number: PA 25 422 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Support for Research Excellence First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed) Apply for PAR 25 415 Funding Number: PAR 25 415 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $125,000 |
| Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed) Apply for PAR 25 322 Funding Number: PAR 25 322 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
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