Opportunity Information: Apply for RFA ES 20 010
The U.S. - India Collaborative Environmental Health Research Program (R01 Clinical Trial Optional), funding opportunity number RFA-ES-20-010, is a National Institutes of Health (NIH) grant program designed to strengthen scientific partnerships between researchers in the United States and India. Its central goal is to support collaborative environmental health research, with a clear emphasis on air pollution and its impacts on human health. Projects funded under this announcement are expected to bring together U.S. and Indian scientists in a meaningful way, encouraging joint planning, shared expertise, and coordinated execution of research that can improve understanding of environmental exposures and related health outcomes in both countries. The activity uses the NIH R01 research project grant mechanism, and clinical trials may be included but are not required, which gives applicants flexibility to propose either observational, mechanistic, exposure science, epidemiology, intervention, or clinical trial work depending on the research question.
This opportunity falls under the broad funding activity category of Environment and Health (CFDA 93.113) and is classified as a discretionary grant. While the core theme is environmental health, the language of the announcement highlights air pollution specifically, suggesting that competitive proposals would likely focus on topics such as ambient and household air pollution, exposure assessment and monitoring, pollutant mixtures, susceptible or high-risk populations, health endpoints linked to air pollution (for example respiratory or cardiovascular outcomes), and approaches that can inform policy, prevention, or risk reduction. Because the program is framed as a U.S.-India collaboration, proposals typically need to demonstrate why the partnership is essential to the work, such as complementary study populations, unique exposure settings, shared methods and data harmonization, capacity building, or comparative analyses that benefit from conducting parallel or coordinated research across both countries.
Eligibility is broad on the U.S. side and includes many standard applicant types: state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; Native American tribal organizations other than federally recognized tribal governments; nonprofits with or without 501(c)(3) status (other than higher education institutions); for-profit organizations (other than small businesses); and small businesses. The announcement also explicitly calls out additional eligible applicant categories, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), eligible federal government agencies, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions. In other words, the program is structured to be accessible to a wide range of U.S.-based organizations capable of conducting rigorous environmental health research and sustaining international collaboration.
At the same time, the eligibility rules for foreign entities are specific. Non-domestic (non-U.S.) entities, described as foreign organizations or foreign institutions, are not eligible to apply as the applicant organization. In addition, non-domestic components of U.S. organizations are not eligible to apply. However, foreign components are allowed as defined in the NIH Grants Policy Statement, which is an important distinction: while a foreign institution generally cannot be the primary applicant under this announcement, the research can include foreign components (such as Indian collaborators, sites, or activities) in a way that aligns with NIH policy and the collaborative intent of the program. In practical terms, this structure supports the U.S.-India collaborative model while keeping the main applicant organization within eligible U.S.-based categories.
Key administrative details included in the source information indicate an original closing date of October 15, 2020, and an award ceiling listed at $200,000. The posting was created on April 29, 2020. The expected number of awards is not specified in the provided data. Overall, this opportunity is best understood as a targeted NIH mechanism to fund well-justified, jointly conducted U.S.-India environmental health studies focused on air pollution, with flexible study design options (including, but not limited to, clinical trials) and a wide range of eligible U.S. applicant organizations, while allowing foreign components under NIH policy to enable substantive collaboration in India.Apply for RFA ES 20 010
- The National Institutes of Health in the environment, health sector is offering a public funding opportunity titled "U.S. - India Collaborative Environmental Health Research Program (R01 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113.
- This funding opportunity was created on 2020-04-29.
- Applicants must submit their applications by 2020-10-15. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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FAQs: U.S. - India Collaborative Environmental Health Research Program (R01 Clinical Trial Optional) (RFA-ES-20-010)
What is this grant opportunity?
This is a National Institutes of Health (NIH) funding opportunity called the U.S. - India Collaborative Environmental Health Research Program (R01 Clinical Trial Optional). It supports collaborative environmental health research carried out by U.S. and Indian researchers, with a strong emphasis on air pollution and human health.
What is the funding opportunity number?
The funding opportunity number is RFA-ES-20-010.
What NIH grant mechanism does this program use?
This program uses the NIH R01 research project grant mechanism.
Are clinical trials required?
No. Clinical trials may be included but are not required. Applicants can propose projects that do or do not include a clinical trial, depending on the research question.
What is the central purpose of the program?
The central goal is to strengthen scientific partnerships between researchers in the United States and India by supporting meaningful, jointly conducted environmental health research.
What scientific focus is emphasized in this announcement?
The announcement highlights air pollution and its impacts on human health as a key emphasis area within environmental health research.
What types of research approaches are allowed under this opportunity?
Projects may include observational studies, mechanistic research, exposure science, epidemiology, interventions, and (optionally) clinical trials. The intent is to provide flexibility so the study design matches the research question.
What kinds of air pollution topics appear most aligned with the announcement?
Based on the description, likely aligned topics include ambient and household air pollution; exposure assessment and monitoring; pollutant mixtures; studies of susceptible or high-risk populations; and health endpoints linked to air pollution such as respiratory or cardiovascular outcomes. Approaches that can inform policy, prevention, or risk reduction are also suggested by the language provided.
What makes a proposal truly "U.S.-India collaborative" under this program?
The program is intended to support meaningful collaboration between U.S. and Indian scientists, including joint planning, shared expertise, and coordinated execution of research. Proposals are typically expected to explain why the partnership is essential, such as access to complementary study populations, unique exposure settings, harmonized methods and data, capacity building, or comparative analyses across both countries.
What is the CFDA number and broad category for this opportunity?
The opportunity is listed under Environment and Health with CFDA 93.113.
What type of grant is this classified as?
It is classified as a discretionary grant.
Who can apply as the applicant organization on the U.S. side?
Eligibility on the U.S. side is broad and includes: state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; Native American tribal organizations other than federally recognized tribal governments; nonprofits with or without 501(c)(3) status (other than higher education institutions); for-profit organizations (other than small businesses); and small businesses.
Are there additional eligible applicant categories explicitly mentioned?
Yes. The description explicitly calls out Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISI); Historically Black Colleges and Universities (HBCUs); Hispanic-serving Institutions; Tribally Controlled Colleges and Universities (TCCUs); eligible federal government agencies; faith-based or community-based organizations; regional organizations; and U.S. territories or possessions.
Can a foreign (non-U.S.) organization apply as the primary applicant?
No. Non-domestic (non-U.S.) entities (foreign organizations or foreign institutions) are not eligible to apply as the applicant organization under this announcement.
Can a non-domestic component of a U.S. organization apply as the applicant?
No. Non-domestic components of U.S. organizations are not eligible to apply as the applicant organization.
Are foreign components allowed in the research?
Yes. Foreign components are allowed as defined in the NIH Grants Policy Statement. This supports the U.S.-India collaborative model by allowing Indian collaborators, sites, or activities as part of the research while keeping the primary applicant organization within eligible U.S.-based categories.
How does the structure support U.S.-India collaboration if foreign entities cannot be the applicant?
The structure allows foreign components under NIH policy, which enables substantive research activities in India and collaboration with Indian scientists, even though the primary applicant organization must be an eligible U.S.-based entity.
What is the listed award ceiling in the provided information?
The provided information lists an award ceiling of $200,000.
What was the original closing date provided?
The original closing date provided is October 15, 2020.
When was the posting created?
The posting was created on April 29, 2020.
Is the expected number of awards stated?
No. The expected number of awards is not specified in the provided information.
What outcomes or impact areas does the program appear to value?
Based on the description, the program supports research that improves understanding of environmental exposures and related health outcomes in both countries, with an emphasis on air pollution. It also suggests interest in work that can inform policy, prevention strategies, or risk reduction approaches.
Does the opportunity limit projects only to air pollution?
The broader theme is environmental health, but the description places clear emphasis on air pollution. Competitive proposals would likely align strongly with air pollution-focused environmental health questions.
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Applicants who have applied for this opportunity (RFA ES 20 010) also looked into and applied for these:
| Funding Opportunity |
|---|
| SBIR E-Learning for HAZMAT and Emergency Response (R43/R44 Clinical Trial Not Allowed) Apply for RFA ES 20 012 Funding Number: RFA ES 20 012 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $100,000 |
| Collaborative Centers in Children's Environmental Health Research and Translation Centers (P2C Clinical Trial Optional) Apply for RFA ES 20 001 Funding Number: RFA ES 20 001 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| RESolution of InflammaTion in EnvirOnmentally Related diseasE (RESTORE) (R01 Clinical Trial Not Allowed) Apply for RFA ES 20 013 Funding Number: RFA ES 20 013 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $350,000 |
| NIEHS SBIR Phase IIB Validation of Sensors for Improved Environmental Exposure Assessment (R44 Clinical Trial Not Allowed) Apply for RFA ES 20 016 Funding Number: RFA ES 20 016 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Pediatric and Reproductive Environmental Health Scholars (PREHS): Strengthening the Pipeline (K12 Clinical Trial Not Allowed) Apply for RFA ES 20 007 Funding Number: RFA ES 20 007 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $450,000 |
| Utilizing In Vitro Functional Genomics Advances for Gene-Environment (G x E) Discovery and Validation (R01 Clinical Trial Not Allowed) Apply for RFA ES 20 018 Funding Number: RFA ES 20 018 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $499,999 |
| Outstanding New Environmental Scientist (ONES) Award (R01 Clinical Trial Optional) Apply for RFA ES 21 001 Funding Number: RFA ES 21 001 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Application of Artificial Intelligence and Machine Learning for Advancing Environmental Health Sciences (R43 Clinical Trial Not Allowed) Apply for RFA ES 21 002 Funding Number: RFA ES 21 002 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Application of Artificial Intelligence and Machine Learning for Advancing Environmental Health Sciences (R41 Clinical Trial Not Allowed) Apply for RFA ES 21 003 Funding Number: RFA ES 21 003 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Immune Development in Early Life (IDEaL) (U19 Clinical Trial Not Allowed) Apply for RFA AI 20 078 Funding Number: RFA AI 20 078 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $1,000,000 |
| Immune Development in Early Life (IDEaL) (U01 Clinical Trial Not Allowed) Apply for RFA AI 20 077 Funding Number: RFA AI 20 077 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $500,000 |
| Transition to Independent Environmental Health Research (TIEHR) Career Award (K01 Clinical Trial Required) Apply for PAR 21 171 Funding Number: PAR 21 171 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Transition to Independent Environmental Health Research (TIEHR) Career Award (K01 Independent Basic Experimental Studies with Humans Required) Apply for PAR 21 170 Funding Number: PAR 21 170 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Transition to Independent Environmental Health Research (TIEHR) Career Award (K01 Clinical Trial Not Allowed) Apply for PAR 21 172 Funding Number: PAR 21 172 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| SBIR E-Learning for HAZMAT and Emergency Response (R43/R44 Clinical Trial Not Allowed) Apply for RFA ES 21 005 Funding Number: RFA ES 21 005 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| CCRP Initiative: Chemical Threat Agent-induced Pulmonary and Ocular Pathophysiological Mechanisms (R01 Clinical Trial Not Allowed) Apply for RFA ES 21 006 Funding Number: RFA ES 21 006 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Innovative Approaches for Improving Environmental Health Literacy (R41/R42 Clinical Trial Not Allowed) Apply for RFA ES 21 009 Funding Number: RFA ES 21 009 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Innovative Approaches for Improving Environmental Health Literacy (R43/R44 Clinical Trial Not Allowed) Apply for RFA ES 21 008 Funding Number: RFA ES 21 008 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Maintaining and Enriching Environmental Epidemiology Cohorts to Support Scientific and Workforce Diversity (U24 Clinical Trial Not Allowed) Apply for RFA ES 22 001 Funding Number: RFA ES 22 001 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $250,000 |
| Revolutionizing Innovative, Visionary Environmental Health Research (RIVER) (R35 Clinical Trial Optional) Apply for RFA ES 22 002 Funding Number: RFA ES 22 002 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
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